Patricia Bath's dedication to a life in medicine began in childhood, when she was first heard about Dr. Albert Schweitzer's service to lepers in the Congo. After excelling in her studies in high school and university and earning awards for scientific research as early as age sixteen, Dr. Bath embarked on a career in medicine. She received her medical degree from Howard University College of Medicine in Washington, D.C., interned at Harlem Hospital from 1968 to 1969, and completed a fellowship in ophthalmology at Columbia University from 1969 to 1970. Following her internship, Dr. Bath completed her training at New York University between 1970 and 1973, where she was the first African American resident in ophthalmology. Bath married and had a daughter Eraka, born 1972. While motherhood became her priority, she also managed to complete a fellowship in corneal transplantation and keratoprosthesis (replacing the human cornea with an artificial one).

As a young intern shuttling between Harlem Hospital and Columbia University, Bath was quick to observe that at the eye clinic in Harlem half the patients were blind or visually impaired. At the eye clinic at Columbia, by contrast, there were very few obviously blind patients. This observation led her to conduct a retrospective epidemiological study, which documented that blindness among blacks was double that among whites. She reached the conclusion that the high prevalence of blindness among blacks was due to lack of access of ophthalmic care. As a result, she proposed a new discipline, known as community ophthalmology, which is now operative worldwide. Community ophthalmology combines aspects of public health, community medicine, and clinical ophthalmology to offer primary care to underserved populations. Volunteers trained as eye workers visit senior centers and daycare programs to test vision and screen for cataracts, glaucoma, and other threatening eye conditions. This outreach has saved the sight of thousands whose problems would otherwise have gone undiagnosed and untreated. By identifying children who need eyeglasses, the volunteers give these children a better chance for success in school.

Bath was also instrumental in bringing ophthalmic surgical services to Harlem Hospital's Eye Clinic, which did not perform eye surgery in 1968. She persuaded her professors at Columbia to operate on blind patients for free, and she volunteered as an assistant surgeon. The first major eye operation at Harlem Hospital was performed in 1970 as a result of her efforts.

In 1974 Bath joined the faculty of UCLA and Charles R. Drew University as an assistant professor of surgery (Drew) and ophthalmology (UCLA). The following year she became the first woman faculty member in the Department of Ophthalmology at UCLA's Jules Stein Eye Institute. When she became the first woman faculty in the department, she was offered an office "in the basement next to the lab animals." She refused the spot. "I didn't say it was racist or sexist. I said it was inappropriate and succeeded in getting acceptable office space. I decided I was just going to do my work." By 1983 she was chair of the ophthalmology residency training program at Drew-UCLA, the first woman in the US to hold such a position.

Despite university policies extolling equality and condemning discrimination, Professor Bath experienced numerous instances of sexism and racism throughout her tenure at both UCLA and Drew. Determined that her scientific endeavors not be obstructed by the "glass ceilings" in the US, she took her research abroad to Europe. Her work was accepted on its merits at the Laser Medical Center of Berlin, West Germany, the Rothschild Eye Institute of Paris, France, and the Loughborough Institute of Technology, England. At those institutions she achieved her "personal best" in research and laser science, the fruits of which are evidenced by her laser patents on eye surgery.

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